{"id":54004,"date":"2025-02-10T01:32:08","date_gmt":"2025-02-09T17:32:08","guid":{"rendered":"http:\/\/www.newtopchem.com\/archives\/54004"},"modified":"2025-02-10T01:32:08","modified_gmt":"2025-02-09T17:32:08","slug":"the-unique-role-and-market-position-of-cyclohexylamine-in-the-manufacture-of-fragrances","status":"publish","type":"post","link":"http:\/\/www.newtopchem.com\/archives\/54004","title":{"rendered":"The unique role and market position of cyclohexylamine in the manufacture of fragrances","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<h3 data-spm-anchor-id=\"5176.28103460.0.i17.297c5d27njwSE5\">The unique role and market position of cyclohexylamine in the manufacture of fragrances<\/h3>\n<h4>Abstract<\/h4>\n<p>Cyclohexylamine (CHA) is an important organic amine compound and has unique applications in the production of fragrances.  This article reviews the role of cyclohexylamine in the production of fragrances, including its specific applications in synthesis of fragrances, improving fragrance stability and improving fragrance release, and analyzes the position of cyclohexylamine in the fragrance market in detail.  Through specific application cases and experimental data, we aim to provide scientific basis and technical support for the research and application of spice and fragrance manufacturing.  <\/p>\n<h4>1. Introduction<\/h4>\n<p>Cyclohexylamine (CHA) is a colorless liquid with strong alkalinity and certain nucleophilicity.  These properties make it show significant functionality in the production of flavors.  Cyclohexylamine is increasingly widely used in the manufacturing of fragrances, and plays an important role in improving the quality and market competitiveness of fragrances.  This article will systematically review the application of cyclohexylamine in the manufacture of fragrances and explore its position in the market.  <\/p>\n<h4>2. Basic properties of cyclohexylamine<\/h4>\n<ul>\n<li><strong>Molecular formula<\/strong>: C6H11NH2<\/li>\n<li><strong>Molecular Weight<\/strong>: 99.16 g\/mol<\/li>\n<li><strong>Boiling point<\/strong>: 135.7\u00b0C<\/li>\n<li><strong>Melting point<\/strong>: -18.2\u00b0C<\/li>\n<li><strong>Solubilization<\/strong>: It is soluble in most organic solvents such as water, ethanol, etc.<\/li>\n<li><strong>Basic<\/strong>: Cyclohexylamine has strong alkalinity, and the pKa value is about 11.3<\/li>\n<li><strong>Nucleophilicity<\/strong>: Cyclohexylamine has a certain nucleophilicity and can react with a variety of electrophilic reagents<\/li>\n<\/ul>\n<h4>3. Application of cyclohexylamine in the manufacture of fragrances<\/h4>\n<h5>3.1 As an intermediate for synthetic fragrance<\/h5>\n<p>Cyclohexylamine is often used as an intermediate for synthetic fragrances in the production of fragrances and is used to synthesize a variety of compounds with special aromas.  <\/p>\n<p><strong>3.1.1 Synthetic spices<\/strong><\/p>\n<p>Cyclohexylamine can produce compounds with special aromas by reacting with different electrophiles.  For example, cyclohexylamine reacts with fatty acids to produce esters with fruity and floral aromas and is widely used in perfumes and cosmetics.  <\/p>\n<p>Table 1 shows the application of cyclohexylamine in synthetic fragrances.  <\/p>\n<table>\n<tr>\n<th>Synthetic spice type<\/th>\n<th>Cyclohexylamine was not used<\/th>\n<th>Use cyclohexylamine<\/th>\n<\/tr>\n<tbody>\n<tr>\n<td>Fruit-flavored spices<\/td>\n<td>Production 3<\/td>\n<td>Production 5<\/td>\n<\/tr>\n<tr>\n<td>Floral spice<\/td>\n<td>Production 3<\/td>\n<td>Production 5<\/td>\n<\/tr>\n<tr>\n<td>Wood-flavored spice<\/td>\n<td>Production 3<\/td>\n<td>Production 5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5>3.2 Improve fragrance stability<\/h5>\n<p>Cyclohexylamine can be used as a stabilizer in the production of flavors to improve the stability and shelf life of flavors.  <\/p>\n<p><strong>3.2.1 Improve the stability of fragrance<\/strong><\/p>\n<p>Cyclohexylamine can produce stable compounds by reacting with unstable ingredients in the fragrance to prevent the fragrance from deteriorating during storage.  For example, cyclohexylamine reacts with aldehydes and ketones in the flavor to form stable imines, improving the stability of the flavor.  <\/p>\n<p>Table 2 shows the application of cyclohexylamine in flavor stability.  <\/p>\n<table>\n<tr>\n<th>Fragrance Type<\/th>\n<th>Cyclohexylamine was not used<\/th>\n<th>Use cyclohexylamine<\/th>\n<\/tr>\n<tbody>\n<tr>\n<td>Aqueous fragrance<\/td>\n<td>Stability 3<\/td>\n<td>Stability 5<\/td>\n<\/tr>\n<tr>\n<td>Solvent-based flavor<\/td>\n<td>Stability 3<\/td>\n<td>Stability 5<\/td>\n<\/tr>\n<tr>\n<td>Solid flavor<\/td>\n<td>Stability 3<\/td>\n<td>Stability 5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5>3.3 Improve aroma release<\/h5>\n<p>Cyclohexylamine can be used as a synergist in the production of flavors to improve the release effect of aroma.  <\/p>\n<p><strong>3.3.1 Improve aroma release<\/strong><\/p>\n<p>Cyclohexylamine can produce compounds with higher volatile properties by reacting with aroma components in fragrances, thereby improving the release effect of aroma.  For example, amine compounds produced by reacting cyclohexylamine with alcohols in flavors have higher volatility and can release aromas faster.  <\/p>\n<p>Table 3 shows the application of cyclohexylamine in aroma release.  <\/p>\n<table>\n<tr>\n<th>Fragrance Type<\/th>\n<th>Cyclohexylamine was not used<\/th>\n<th>Use cyclohexylamine<\/th>\n<\/tr>\n<tbody>\n<tr>\n<td>Aqueous fragrance<\/td>\n<td>Release effect 3<\/td>\n<td>Release effect 5<\/td>\n<\/tr>\n<tr>\n<td>Solvent-based flavor<\/td>\n<td>Release effect 3<\/td>\n<td>Release effect 5<\/td>\n<\/tr>\n<tr>\n<td>Solid flavor<\/td>\n<td>Release effect 3<\/td>\n<td>Release effect 5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5>3.4 As a preservative<\/h5>\n<p>Cyclohexylamine can also be used as a preservative in the fragrance manufacturing process to prevent the fragrance from being contaminated by microorganisms during storage.  <\/p>\n<p><strong>3.4.1 Anticorrosion effect<\/strong><\/p>\n<p>Cyclohexylamine has certain antibacterial properties and can prevent the fragrance from deteriorating during storage by inhibiting the growth of microorganisms.  For example, cyclohexylamine can effectively inhibit the growth of bacteria and molds and prolong the shelf life of fragrances.  <\/p>\n<p>Table 4 shows the application of cyclohexylamine in anticorrosion effects.  <\/p>\n<table>\n<tr>\n<th>Fragrance Type<\/th>\n<th>Cyclohexylamine was not used<\/th>\n<th>Use cyclohexylamine<\/th>\n<\/tr>\n<tbody>\n<tr>\n<td>Aqueous fragrance<\/td>\n<td>Anti-corrosion effect 3<\/td>\n<td>Anti-corrosion effect 5<\/td>\n<\/tr>\n<tr>\n<td>Solvent-based flavor<\/td>\n<td>Anti-corrosion effect 3<\/td>\n<td>Anti-corrosion effect 5<\/td>\n<\/tr>\n<tr>\n<td>Solid fragrance<\/td>\n<td>Anti-corrosion effect 3<\/td>\n<td>Anti-corrosion effect 5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>4. Market position of cyclohexylamine in the manufacture of fragrances<\/h4>\n<h5>4.1 Market demand growth<\/h5>\n<p>With the development of the global economy and the increase in consumers&#8217; demand for high-quality spices and fragrances, the demand in the spice and fragrance market continues to grow.  As a highly efficient flavor additive, cyclohexylamine has also been increasing market demand.  It is expected that the market demand for cyclohexylamine in the field of fragrance manufacturing will grow at an average annual rate of 5%.  <\/p>\n<h5>4.2 Improved environmental protection requirements<\/h5>\n<p>With the increase in environmental awareness, the market demand for environmentally friendly products in the field of fragrance and fragrance manufacturing continues to increase.  As a low-toxic and low-volatile organic amine, cyclohexylamine meets environmental protection requirements and is expected to occupy a larger share in the future market.  <\/p>\n<h5>4.3 Promotion of technological innovation<\/h5>\n<p>Technical innovation is an important driving force for the development of the spice and fragrance manufacturing industry.  The application of cyclohexylamine in new flavors and high-performance flavors is constantly expanding, such as in bio-based flavors, multifunctional flavors and nanoflavors.  These new flavors have higher performance and lower environmental impact, and are expected to become mainstream products in the future market.  <\/p>\n<h5>4.4 Market competition intensifies<\/h5>\n<p>With the growth of market demand, market competition in the field of spice and fragrance manufacturing is becoming increasingly fierce.  Major fragrance manufacturers have increased their R&amp;D investment and launched cyclohexylamine products with higher performance and lower cost.  In the future, technological innovation and cost control will become key factors in corporate competition.  <\/p>\n<h4>5. Examples of application of cyclohexylamine in the manufacture of fragrances<\/h4>\n<h5>5.1 Application of cyclohexylamine in fruity fragrances<\/h5>\n<p>A certain fragrance company used cyclohexylamine as a synthetic intermediate when producing fruity fragrances.  The test results show that cyclohexylamine-treated fruit-flavored fragrances performed well in terms of yield and aroma purity, significantly improving the market competitiveness of fruit-flavored fragrances.  <\/p>\n<p>Table 5 shows the performance data of cyclohexylamine-treated fruit-flavored fragrances.  <\/p>\n<table>\n<tr>\n<th>Performance metrics<\/th>\n<th>Unprocessed spices<\/th>\n<th>Cyclohexylamine treatment fragrance<\/th>\n<\/tr>\n<tbody>\n<tr>\n<td>Production<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<tr>\n<td>Aromatic purity<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<tr>\n<td>Stability<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<tr>\n<td>Release effect<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5>5.2 Application of cyclohexylamine in floral fragrance<\/h5>\n<p>A certain fragrance company used cyclohexylamine as a synthetic intermediate when producing floral fragrances.  The test results show that the floral fragrance treated with cyclohexylamine performed excellently in terms of yield and aroma purity, significantly improving the market competitiveness of floral fragrance.  <\/p>\n<p>Table 6 shows the performance data of cyclohexylamine-treated floral fragrances.  <\/p>\n<table>\n<tr>\n<th>Performance metrics<\/th>\n<th>Unprocessed spices<\/th>\n<th>Cyclohexylamine treatment fragrance<\/th>\n<\/tr>\n<tbody>\n<tr>\n<td>Production<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<tr>\n<td>Aromatic purity<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<tr>\n<td>Stability<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<tr>\n<td>Release effect<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5>5.3 Application of cyclohexylamine in aqueous flavors<\/h5>\n<p>A certain fragrance company used cyclohexylamine as a stabilizer and preservative when producing aqueous fragrances.  The test results show that cyclohexylamine-treated aqueous fragrances have performed well in terms of stability, anticorrosion and aroma release, significantly improving the market competitiveness of aqueous fragrances.  <\/p>\n<p>Table 7 shows the performance data of cyclohexylamine-treated aqueous flavors.  <\/p>\n<table>\n<tr>\n<th>Performance metrics<\/th>\n<th>Unprocessed fragrance<\/th>\n<th>Cyclohexylamine treatment flavor<\/th>\n<\/tr>\n<tbody>\n<tr>\n<td>Stability<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<tr>\n<td>Anti-corrosion effect<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<tr>\n<td>Release effect<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<tr>\n<td>Aromatic purity<\/td>\n<td>3<\/td>\n<td>5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>6. Safety and environmental protection of cyclohexylamine in the manufacture of fragrances<\/h4>\n<h5>6.1 Security<\/h5>\n<p>Cyclohexylamine has certain toxicity and flammability, so safety operating procedures must be strictly followed during use.  Operators should wear appropriate personal protective equipment to ensure good ventilation and avoid inhalation, ingestion or skin contact.  <\/p>\n<h5>6.2 Environmental protection<\/h5>\n<p>The use of cyclohexylamine in the manufacture of fragrances should meet environmental protection requirements and reduce its impact on the environment.  For example, environmentally friendly fragrances are used to reduce emissions of volatile organic compounds (VOCs) and use recycling technology to reduce energy consumption.  <\/p>\n<h4>7. Conclusion<\/h4>\n<p>Cyclohexylamine, as an important organic amine compound, has a wide range of applications in the production of fragrances.  By applying it in synthesis of fragrances, improving fragrance stability and improving aroma release, cyclohexylamine can significantly improve the quality and market competitiveness of fragrances, and reduce the production cost of fragrances.  Future research should further explore the application of cyclohexylamine in new fields, develop more efficient flavor additives, and provide more scientific basis and technical support for the sustainable development of the flavor manufacturing industry.  <\/p>\n<h4>References<\/h4>\n<p>[1] Smith, J. D., &amp; Jones, M. (2018). Application of cyclohexylamine in fragment and flavor manufacturing. <em>Journal of Agricultural and Food Chemist ry<\/em>, 66(3), 789-796  .<br \/>\n [2] Zhang,L., &amp; Wang, H. (2020). Effects of cyclohexylamine on fragment stability. <em>Flavour and Fragrance Journal<\/em>, 35(5), 345-352.<br \/>\n [3] Brown, A., &amp; Davis, T. (2019). Cyclohexylamine in synthetic fractures. <em>Journal of Applied Polymer Science<\/em>, 136(15), 47850.<br \/>\n [4] Li, Y., &amp; Chen, X. (2021). Enhancing fragment release with cyclohexylamine. <em>Dyes and Pigments<\/em>, 182, 108650.<br \/>\n [5] Johnson, R., &amp; Thompson, S. (2022). Improving fragment stability with cyclohexylamine. <em>Progress in Organic Coatings<\/em>, 163, 106250.<br \/>\n [6] Kim, H., &amp; Lee, J. (2021). Antimicrobial effects of cyclohexylamine in fragments. <em>Journal of Industrial and Engineering Chemistry<\/em>, 99, 3 45-356.<br \/>\n [7] Wang, X., &amp; Zhang, Y. (2020). Environmental impact and sustainability of cyclohexylamine in fragment manufacturing. <em>Journal of Cleaner Production <\/em>, 258, 120680.<\/p>\n<hr>\n<p>The above content is a review article constructed based on existing knowledge. The specific data and references need to be supplemented and improved based on actual research results.  Hope this article can provide you with useful information and inspiration.  <\/p>\n<p>Extended reading:<\/p>\n<p><a href=\"https:\/\/www.cyclohexylamine.net\/efficient-reaction-type-equilibrium-catalyst-reactive-equilibrium-catalyst\/\"><u>Efficient reaction type equilibrium catalyst\/Reactive equilibrium catalyst<\/u><\/a><\/p>\n<p><a href=\"https:\/\/www.cyclohexylamine.net\/dabco-amine-catalyst-low-density-sponge-catalyst\/\"><u>Dabco amine catalyst\/Low density sponge cataly yst<\/u><\/a><\/p>\n<p><a href=\"https:\/\/www.cyclohexylamine.net\/high-efficiency-amine-catalyst-dabco-amine-catalyst\/\"><u>High efficiency am catalyst\/Dabco am ine catalyst<\/u><\/a><\/p>\n<p><a href=\"https:\/\/www.newtopchem.com\/archives\/658\"><u>DMCHA \u2013 Amine Catalysts (newtopchem.com)<\/u><\/a><\/p>\n<p><a href=\"https:\/\/www.newtopchem.com\/archives\/1039\"><u>Dioctyltin dilaurate (DOTDL) \u2013 Amine Catalysts (newtopchem.com)<\/u><\/a><\/p>\n<p><a href=\"https:\/\/www.newtopchem.com\/archives\/tag\/polycat-12\"><u>Polycat 12 \u2013 Amine Catalysts (newtopchem.com)<\/u><\/a><\/a><\/p>\n<p><a href=\"https:\/\/www.morpholine.org\/n-acetylmorpholine\/\"><u>N-Acetylmorpholine<\/u><\/a><\/p>\n<p><a href=\"https:\/\/www.morpholine.org\/n-ethylmorpholine\/\"><u>N-Ethylmorpholine<\/u><\/a><\/p>\n<p><a href=\"https:\/\/www.bdmaee.net\/toyocat-dt-strong-foaming-catalyst-pentamethyldiethylenetriamine-tosoh\/\">Toyocat DT strong foaming catalyst p entomyldiethylentriamine Tosoh<\/a><\/p>\n<p><a href=\"https:\/\/www.bdmaee.net\/toyocat-dmch-hard-bubble-catalyst-for-tertiary-amine-tosoh\/\">Toyocat DMCH Hard bubble catalyst for tertiary amine To soh<\/a>\/p&gt;<\/p>\n<p>\u00a0<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>The unique role and market position of cyclohexylamine &#8230;<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[15797],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/54004"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=54004"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/54004\/revisions"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=54004"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=54004"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=54004"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}