<\/p>\n
Structural formula<\/p>\n
2-Amino-4,6-pyrimidinediol<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
CAS number:<\/b>56-09-7<\/p>\n
MDL number:<\/b>MFCD00006094<\/p>\n
EINECS number:<\/b>200-256-5<\/p>\n
RTECS number:<\/b>UW7361000<\/p>\n
BRN number:<\/b>510297<\/p>\n
PubChem number:<\/b>24890936<\/p>\nPhysical property data<\/h2>\n
1. Properties: White amorphous powder<\/p>\n
2. Density (g\/mL, 25\/4\u2103): Undetermined<\/p>\n
3. Relative vapor density (g\/mL, air=1): Not determined<\/p>\n
4. Melting point (decomposition, \u00baC): 330<\/p>\n
5. Boiling point (\u00baC, normal pressure): Not determined Determined<\/p>\n
6. Boiling point (\u00baC, 5.2kPa): Not determined<\/p>\n
7. Refractive index: Not determined<\/p>\n
8. Flash point (\u00baC): Not determined Determined<\/p>\n
9. Specific rotation (\u00ba): Undetermined<\/p>\n
10. Autoignition point or ignition temperature (\u00baC): Undetermined<\/p>\n
11. Vapor Pressure (kPa, 25\u00baC): Undetermined<\/p>\n
12. Saturated vapor pressure (kPa, 60\u00baC): Undetermined<\/p>\n
13. Heat of combustion (KJ\/mol): Undetermined<\/p>\n
p><\/p>\n
14. Critical temperature (\u00baC): Undetermined<\/p>\n
15. Critical pressure (KPa): Undetermined<\/p>\n
16. Oil-water (octanol\/water) partition coefficient Logarithmic value of p><\/p>\n
19. Solubility: Insoluble in water, insoluble in common organic solvents, soluble in alkaline aqueous solutions, absorbing water in humid air. <\/p>\n<\/p>\n
\n None\n <\/p>\n
1. Molar refractive index: 30.43<\/p>\n
2. Molar volume (cm3<\/sup>\/mol): 75.0<\/p>\n3. Isotonic specific volume (90.2K ): 251.4<\/p>\n4. Surface tension (dyne\/cm): 126.1<\/p>\n5. Polarizability (10-24<\/sup>cm3<\/sup>): 12.06<\/p>\n<\/p>\nCompute chemical data<\/h2>\n1. Hydrophobic parameter calculation reference value (XlogP): -1.4<\/p>\n2. Number of hydrogen bond donors: 3<\/p>\n3. Number of hydrogen bond acceptors: 4<\/p>\n p><\/p>\n4. Number of rotatable chemical bonds: 0<\/p>\n5. Number of tautomers: 5<\/p>\n6. Topological molecular polar surface area (TPSA): 87.7<\/p>\n7. Number of heavy atoms: 9<\/p>\n8. Surface charge: 0<\/p>\n9. Complexity: 206<\/p>\n10. Isotopic atoms Number\ufffd\ufffd: 0<\/p>\n11. Determine the number of atomic stereocenters: 0<\/p>\n12. Uncertain number of atomic stereocenters: 0<\/p>\n13. Determine chemical bonds Number of stereocenters: 0<\/p>\n14. Number of stereocenters of uncertain chemical bonds: 0<\/p>\n15. Number of covalent bond units: 1<\/p>\n<\/p>\nProperties and stability<\/h2>\n\n None\n <\/p>\nStorage method<\/h2>\nStored sealed and protected from light. <\/p>\n<\/p>\nSynthesis method<\/h2>\nThe preparation method is to add sodium ethoxide and diethyl malonate into the reaction kettle, then add guanidine nitrate, stir, and heat to reflux for 7 hours, cool to room temperature and discharge, the filtrate is distilled to recover absolute ethanol, and filtered The cake is then put into the water washing kettle, stirred with water, and heated to 80\u00b0C. After it is completely dissolved, slowly add concentrated hydrochloric acid, adjust the pH value to neutral, filter and discharge the material to obtain the finished product. <\/p>\n<\/p>\nPurpose<\/h2>\n2-Amino-4,6-dihydroxypyrimidine is an intermediate for the preparation of 2-amino-4,6-dimethoxypyrimidine, which can be used to produce sulfonylurea herbicides such as bensulfuron-methyl and pyridine. Cisulfuron-methyl, nicosulfuron-methyl, etc. <\/p>\nUsed as an intermediate for the herbicides bensulfuron-methyl and pyrazosulfuron-methyl. <\/p>\nImportant pharmaceutical intermediates. <\/p>\nUsed for the synthesis of ADCP, ACMP, and ADMP. <\/p>\n<\/p>\n extended-reading:https:\/\/www.newtopchem.com\/archives\/40470<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/246-trisdimethylaminomethylphenol-cas90-72-2-dabco-tmr-30\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/dabco-xd-102-dabco-amine-catalyst-amine-catalyst\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/niax-potassium-acetate-trimer-catalyst-momentive\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/NNN-trimethyl-N-hydroxyethyl-bisaminoethyl-ether-CAS-83016-70-0-Jeffcat-ZF-10.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44742<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44057<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/-MP602-delayed-amine-catalyst-non-emission-amine-catalyst.pdf<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/cas111-41-1\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/spraying-composite-amine-catalyst-nt-cat-pt1003-pt1003\/<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 0176 Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":48905,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[6005,15342],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48906"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=48906"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48906\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/48905"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=48906"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=48906"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=48906"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
3. Isotonic specific volume (90.2K ): 251.4<\/p>\n
4. Surface tension (dyne\/cm): 126.1<\/p>\n
5. Polarizability (10-24<\/sup>cm3<\/sup>): 12.06<\/p>\n<\/p>\nCompute chemical data<\/h2>\n1. Hydrophobic parameter calculation reference value (XlogP): -1.4<\/p>\n2. Number of hydrogen bond donors: 3<\/p>\n3. Number of hydrogen bond acceptors: 4<\/p>\n p><\/p>\n4. Number of rotatable chemical bonds: 0<\/p>\n5. Number of tautomers: 5<\/p>\n6. Topological molecular polar surface area (TPSA): 87.7<\/p>\n7. Number of heavy atoms: 9<\/p>\n8. Surface charge: 0<\/p>\n9. Complexity: 206<\/p>\n10. Isotopic atoms Number\ufffd\ufffd: 0<\/p>\n11. Determine the number of atomic stereocenters: 0<\/p>\n12. Uncertain number of atomic stereocenters: 0<\/p>\n13. Determine chemical bonds Number of stereocenters: 0<\/p>\n14. Number of stereocenters of uncertain chemical bonds: 0<\/p>\n15. Number of covalent bond units: 1<\/p>\n<\/p>\nProperties and stability<\/h2>\n\n None\n <\/p>\nStorage method<\/h2>\nStored sealed and protected from light. <\/p>\n<\/p>\nSynthesis method<\/h2>\nThe preparation method is to add sodium ethoxide and diethyl malonate into the reaction kettle, then add guanidine nitrate, stir, and heat to reflux for 7 hours, cool to room temperature and discharge, the filtrate is distilled to recover absolute ethanol, and filtered The cake is then put into the water washing kettle, stirred with water, and heated to 80\u00b0C. After it is completely dissolved, slowly add concentrated hydrochloric acid, adjust the pH value to neutral, filter and discharge the material to obtain the finished product. <\/p>\n<\/p>\nPurpose<\/h2>\n2-Amino-4,6-dihydroxypyrimidine is an intermediate for the preparation of 2-amino-4,6-dimethoxypyrimidine, which can be used to produce sulfonylurea herbicides such as bensulfuron-methyl and pyridine. Cisulfuron-methyl, nicosulfuron-methyl, etc. <\/p>\nUsed as an intermediate for the herbicides bensulfuron-methyl and pyrazosulfuron-methyl. <\/p>\nImportant pharmaceutical intermediates. <\/p>\nUsed for the synthesis of ADCP, ACMP, and ADMP. <\/p>\n<\/p>\n extended-reading:https:\/\/www.newtopchem.com\/archives\/40470<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/246-trisdimethylaminomethylphenol-cas90-72-2-dabco-tmr-30\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/dabco-xd-102-dabco-amine-catalyst-amine-catalyst\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/niax-potassium-acetate-trimer-catalyst-momentive\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/NNN-trimethyl-N-hydroxyethyl-bisaminoethyl-ether-CAS-83016-70-0-Jeffcat-ZF-10.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44742<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44057<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/-MP602-delayed-amine-catalyst-non-emission-amine-catalyst.pdf<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/cas111-41-1\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/spraying-composite-amine-catalyst-nt-cat-pt1003-pt1003\/<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 0176 Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":48905,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[6005,15342],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48906"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=48906"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48906\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/48905"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=48906"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=48906"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=48906"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
1. Hydrophobic parameter calculation reference value (XlogP): -1.4<\/p>\n
2. Number of hydrogen bond donors: 3<\/p>\n
3. Number of hydrogen bond acceptors: 4<\/p>\n
4. Number of rotatable chemical bonds: 0<\/p>\n
5. Number of tautomers: 5<\/p>\n
6. Topological molecular polar surface area (TPSA): 87.7<\/p>\n
7. Number of heavy atoms: 9<\/p>\n
8. Surface charge: 0<\/p>\n
9. Complexity: 206<\/p>\n
10. Isotopic atoms Number\ufffd\ufffd: 0<\/p>\n
11. Determine the number of atomic stereocenters: 0<\/p>\n
12. Uncertain number of atomic stereocenters: 0<\/p>\n
13. Determine chemical bonds Number of stereocenters: 0<\/p>\n
14. Number of stereocenters of uncertain chemical bonds: 0<\/p>\n
15. Number of covalent bond units: 1<\/p>\n<\/p>\n
Stored sealed and protected from light. <\/p>\n<\/p>\n
The preparation method is to add sodium ethoxide and diethyl malonate into the reaction kettle, then add guanidine nitrate, stir, and heat to reflux for 7 hours, cool to room temperature and discharge, the filtrate is distilled to recover absolute ethanol, and filtered The cake is then put into the water washing kettle, stirred with water, and heated to 80\u00b0C. After it is completely dissolved, slowly add concentrated hydrochloric acid, adjust the pH value to neutral, filter and discharge the material to obtain the finished product. <\/p>\n<\/p>\n
2-Amino-4,6-dihydroxypyrimidine is an intermediate for the preparation of 2-amino-4,6-dimethoxypyrimidine, which can be used to produce sulfonylurea herbicides such as bensulfuron-methyl and pyridine. Cisulfuron-methyl, nicosulfuron-methyl, etc. <\/p>\n
Used as an intermediate for the herbicides bensulfuron-methyl and pyrazosulfuron-methyl. <\/p>\n
Important pharmaceutical intermediates. <\/p>\n
Used for the synthesis of ADCP, ACMP, and ADMP. <\/p>\n<\/p>\n
extended-reading:https:\/\/www.newtopchem.com\/archives\/40470<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/246-trisdimethylaminomethylphenol-cas90-72-2-dabco-tmr-30\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/dabco-xd-102-dabco-amine-catalyst-amine-catalyst\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/niax-potassium-acetate-trimer-catalyst-momentive\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/NNN-trimethyl-N-hydroxyethyl-bisaminoethyl-ether-CAS-83016-70-0-Jeffcat-ZF-10.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44742<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44057<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/-MP602-delayed-amine-catalyst-non-emission-amine-catalyst.pdf<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/cas111-41-1\/<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/spraying-composite-amine-catalyst-nt-cat-pt1003-pt1003\/<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 0176 Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":48905,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[6005,15342],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48906"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=48906"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48906\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/48905"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=48906"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=48906"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=48906"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Structural formula Business number 0176 Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":48905,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[6005,15342],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48906"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=48906"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48906\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/48905"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=48906"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=48906"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=48906"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
![\"2-amino-4,6-dihydroxypyrimidine](\"http:\/\/www.newtopchem.com\/wp-content\/uploads\/2024\/05\/6744a2dca353426fa2b8d6bb5b7c5f72.gif\")
<\/p>\n<\/p>\n