{"id":48821,"date":"2024-05-16T17:38:28","date_gmt":"2024-05-16T09:38:28","guid":{"rendered":"http:\/\/www.newtopchem.com\/archives\/48821"},"modified":"2024-05-16T17:38:28","modified_gmt":"2024-05-16T09:38:28","slug":"thioridazine","status":"publish","type":"post","link":"http:\/\/www.newtopchem.com\/archives\/48821","title":{"rendered":"thioridazine","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-48820\" src=\"http:\/\/www.newtopchem.com\/wp-content\/uploads\/2024\/05\/b2ab4b604ea845dcbcbc42769dbe04a5.gif\" width=\"284\" height=\"227\" alt=\"Thioridazine structural formula\" \/><\/p>\n<p>Structural formula<\/p>\n<table class=\"summary-table table table-striped table-bordered\">\n<col width=\"90\" \/>\n<tbody>\n<tr>\n<th scope=\"row\">Business number<\/th>\n<td>013U<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular formula<\/th>\n<td>C21H26N2S2<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular weight<\/th>\n<td>370.57<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">label<\/th>\n<td>\n<p>                         thioridazine,<\/p>\n<p>                         10-[2-(1-methyl-2-piperidinyl)ethyl]-2-methylthio-10H-phenothiazine,<\/p>\n<p>                         thioridazine,<\/p>\n<p>                         Thiopridine,<\/p>\n<p>                         thioetherazine,<\/p>\n<p>                         10-((1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin,<\/p>\n<p>                         10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-10h-phenothiazin,<\/p>\n<p>                         10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin,<\/p>\n<p>                         10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul class=\"nav nav-tabs\">\n<li class=\"active\"><a href=\"#bh\">Numbering system<\/a><\/li>\n<li><a href=\"#wx\">Physical property data<\/a><\/li>\n<li><a href=\"#dl\">Toxicological data<\/a><\/li>\n<li><a href=\"#st\">Ecological data<\/a><\/li>\n<li><a href=\"#fz\">Molecular structure data<\/a><\/li>\n<li><a href=\"#js\">Computing chemical data<\/a><\/li>\n<li class=\"dropdown pull-right\">\n                     <a href=\"\" class=\"dropdown-toggle\">More <span class=\"caret\"><\/span><\/a><\/p>\n<ul class=\"dropdown-menu\" role=\"menu\">\n<li><a href=\"#xz\">Properties and Stability<\/a><\/li>\n<li><a href=\"#zc\">Storage method<\/a><\/li>\n<li><a href=\"#hc\">Synthesis method<\/a><\/li>\n<li><a href=\"#yt\">Purpose<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"bh\">Numbering system<\/h2>\n<p><b>CAS number:<\/b>50-52-2<\/p>\n<p><b>MDL number:<\/b>MFCD00242875<\/p>\n<p><b>EINECS number:<\/b>200-044-2<\/p>\n<p><b>RTECS number:<\/b>None<\/p>\n<p><b>BRN number:<\/b>None<\/p>\n<p><b>PubChem ID:<\/b>None<\/p>\n<h2 id=\"wx\">Physical property data<\/h2>\n<p><p>1. Properties: Crystal.  <\/p>\n<p>2. Density (g\/mL, 25\/4\u2103): Undetermined<\/p>\n<p>3. Relative vapor density (g\/mL, air=1): Undetermined<\/p>\n<p>4. Melting point (\u00baC): 72\uff5e74\u2103<\/p>\n<p>5. Boiling point (\u00baC, normal pressure): Undetermined<\/p>\n<p>6. Boiling point (\u00baC, 5.2 kPa)  : Undetermined<\/p>\n<p>7. Refractive index: Undetermined<\/p>\n<p>8. Flash point (\u00baC): Undetermined<\/p>\n<p>9. Specific rotation (\u00ba):  Undetermined<\/p>\n<p>10. Autoignition point or ignition temperature (\u00baC): Undetermined<\/p>\n<p>11. Vapor pressure (kPa, 25 \u00baC): Undetermined<\/p>\n<p>  12. Saturated vapor pressure (kPa, 60 \u00baC): Undetermined<\/p>\n<p>13. Heat of combustion (KJ\/mol): Undetermined<\/p>\n<p>14. Critical temperature (\u00baC): Undetermined  <\/p>\n<p>15. Critical pressure (KPa): Undetermined<\/p>\n<p>16. Log value of oil-water (octanol\/water) partition coefficient: Undetermined<\/p>\n<p>17.  Explosion upper limit (%, V\/V): Undetermined<\/p>\n<p>18. Explosion lower limit (%, V\/V): Undetermined<\/p>\n<p>19. Solubility: Undetermined<\/p>\n<\/p>\n<h2 id=\"dl\">Toxicological data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"st\">Ecological data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"fz\">Molecular structure data<\/h2>\n<p><p>1. Molar refractive index: 112.80<\/p>\n<p>2. Molar volume (cm<sup>3<\/sup>\/mol): 299.5<\/p>\n<p>3. Isotonic specific volume (90.2K): 829.1<\/p>\n<p>4. Surface  Tension (dyne\/cm): 58.6<\/p>\n<p>5. Polarizability (10-24cm3): 44.71<\/p>\n<\/p>\n<h2 id=\"js\">Compute chemical data<\/h2>\n<p><p>1. Reference value for hydrophobic parameter calculation (XlogP): None<\/P><\/p>\n<p>2. Number of hydrogen bond donors: 0<\/p>\n<p>3. Number of hydrogen bond acceptors: 4<\/p>\n<p>4. Number of rotatable chemical bonds: 4<\/p>\n<p>5. Number of tautomers: none<\/p>\n<p>6. Topological molecule polar surface area 57.1<\/p>\n<p>7. Number of heavy atoms: 25<\/p>\n<p>8. Surface charge: 0<\/p>\n<p>9. Complexity: 432<\/p>\n<p>10. Number of isotope atoms: 0<\/p>\n<p>11. Determine the number of atomic stereocenters: 0<\/p>\n<p>12. Uncertain number of atomic stereocenters: 1<\/p>\n<p>13. Determine the number of chemical bond stereocenters: 0  <\/p>\n<p>14. Number of uncertain chemical bond stereocenters: 0<\/p>\n<p>15. Number of covalent bond units: 1<\/p>\n<\/p>\n<h2 id=\"xz\">Properties and stability<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"zc\">Storage method<\/h2>\n<p><p>This product should be sealed and stored in a dry place away from light.  <\/p>\n<\/p>\n<h2 id=\"hc\">Synthesis method<\/h2>\n<p>\n     <span style=\"font-family:\u5b8b\u4f53;font-size:x-small\">This product is crystallized from acetone<\/span>\n     <\/p>\n<h2 id=\"yt\">Purpose<\/h2>\n<p>\n     This product has a sedative effect and is used for patients with neurosis, alcohol dependence withdrawal, chorea, mental disorders accompanied by tension, anxiety and somatosensory abnormalities, and schizophrenia patients. It also has obvious anticholinergic effects.  The preparation is a tablet.  <\/p>\n<p>     extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/44024\">https:\/\/www.newtopchem.com\/archives\/44024<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/95\">https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/95<\/a><\/br>extended-reading:<a href=\"https:\/\/www.cyclohexylamine.net\/pentamethyldipropene-triamine-cas-3855-32-1\/\">https:\/\/www.cyclohexylamine.net\/pentamethyldipropene-triamine-cas-3855-32-1\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/wp-content\/uploads\/2020\/06\/30.jpg\">https:\/\/www.bdmaee.net\/wp-content\/uploads\/2020\/06\/30.jpg<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/lupragen-n204\/\">https:\/\/www.bdmaee.net\/lupragen-n204\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/fomrez-ul-29-catalyst-octylmercaptan-stannous-momentive\/\">https:\/\/www.bdmaee.net\/fomrez-ul-29-catalyst-octylmercaptan-stannous-momentive\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/31-1.jpg\">https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/31-1.jpg<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/44561\">https:\/\/www.newtopchem.com\/archives\/44561<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/monobutylzinntrichlorid\/\">https:\/\/www.bdmaee.net\/monobutylzinntrichlorid\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/1103\">https:\/\/www.newtopchem.com\/archives\/1103<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Structural formula Business number 013U Molecular formu&#8230;<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":48820,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[15314],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48821"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=48821"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48821\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/48820"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=48821"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=48821"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=48821"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}