{"id":47879,"date":"2024-04-23T15:01:01","date_gmt":"2024-04-23T07:01:01","guid":{"rendered":"http:\/\/www.newtopchem.com\/archives\/47879"},"modified":"2024-04-23T15:01:01","modified_gmt":"2024-04-23T07:01:01","slug":"17%ce%b1-hydroxyprogesterone","status":"publish","type":"post","link":"http:\/\/www.newtopchem.com\/archives\/47879","title":{"rendered":"17\u03b1-hydroxyprogesterone","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p>Structural formula<\/p>\n<table class=\"summary-table table table-striped table-bordered\">\n<col width=\"90\" \/>\n<tbody>\n<tr>\n<th scope=\"row\">Business number<\/th>\n<td>01FG<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular formula<\/th>\n<td>C21H30O3<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular weight<\/th>\n<td>330.46<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">label<\/th>\n<td>\n<p>                         17\u03b1-Hydroxyprogesterone,<\/p>\n<p>                         17\u03b1-hydroxypregnant-4-ene-3,20-dione,<\/p>\n<p>                         Hydroxyprogesterone,<\/p>\n<p>                         Pregnant-4-en-17\u03b1-ol-3,20-dione,<\/p>\n<p>                         17hydroxyprogesterone,<\/p>\n<p>                         17\u03b1-Hydroxyprogesterone,<\/p>\n<p>                         17\u03b1-Hydroxypregnenedione,<\/p>\n<p>                         17-hydroxypregnanthin,<\/p>\n<p>                         4-Pregnen-17\u03b1-ol-3,20-dione,<\/p>\n<p>                         17\u03b1-Hydroxy-4-pregnene-3,20-dione<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul class=\"nav nav-tabs\">\n<li class=\"active\"><a href=\"#bh\">Numbering system<\/a><\/li>\n<li><a href=\"#wx\">Physical property data<\/a><\/li>\n<li><a href=\"#dl\">Toxicological data<\/a><\/li>\n<li><a href=\"#st\">Ecological data<\/a><\/li>\n<li><a href=\"#fz\">Molecular structure data<\/a><\/li>\n<li><a href=\"#js\">Computing chemical data<\/a><\/li>\n<li class=\"dropdown pull-right\">\n                     <a href=\"\" class=\"dropdown-toggle\">More <span class=\"caret\"><\/span><\/a><\/p>\n<ul class=\"dropdown-menu\" role=\"menu\">\n<li><a href=\"#xz\">Properties and Stability<\/a><\/li>\n<li><a href=\"#zc\">Storage method<\/a><\/li>\n<li><a href=\"#hc\">Synthesis method<\/a><\/li>\n<li><a href=\"#yt\">Purpose<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"bh\">Numbering system<\/h2>\n<p><b>CAS number:<\/b>68-96-2<\/p>\n<p><b>MDL number:<\/b>MFCD00003659<\/p>\n<p><b>EINECS number:<\/b>200-699-4<\/p>\n<p><b>RTECS number:<\/b>TU5060000<\/p>\n<p><b>BRN number:<\/b>3218109<\/p>\n<p><b>PubChem number:<\/b>24278469<\/p>\n<h2 id=\"wx\">Physical property data<\/h2>\n<p>\n     1. Character: White diamond-shaped or hexagonal leaf-shaped crystals.  2. Density (g\/mL, 25\/4\u2103): Uncertain<\/p>\n<p>3. Relative vapor density (g\/mL, air=1): Uncertain<\/p>\n<p>4. Melting point (\u00baC): 221\u2103 (  219-220\u2103).  5. Boiling point (\u00baC, normal pressure): Uncertain<\/p>\n<p>6. Boiling point (\u00baC, 5.2kPa): Uncertain<\/p>\n<p>7. Refractive index: 90 \u00b0 (C=1, CHCl3)<\/p>\n<p>  p&gt;<\/p>\n<p>8. Flash point (\u00baC): Uncertain<\/p>\n<p>9. Specific rotation (\u00ba): Uncertain<\/p>\n<p>10. Autoignition point or ignition temperature (\u00baC  ): Uncertain<\/p>\n<p>11. Vapor pressure (kPa, 25\u00baC): Uncertain<\/p>\n<p>12. Saturated vapor pressure (kPa, 60\u00baC): Uncertain<\/p>\n<p>  13. Heat of combustion (KJ\/mol): Uncertain<\/p>\n<p>14. Critical temperature (\u00baC): Uncertain<\/p>\n<p>15. Critical pressure (KPa): Uncertain<\/p>\n<p>16. The logarithmic value of the oil-water (octanol\/water) partition coefficient: Uncertain<\/p>\n<p>17. The upper limit of explosion (%, V\/V): Uncertain<\/p>\n<p>18.  Lower explosion limit (%, V\/V): Uncertain<\/p>\n<p>19. Solubility: Easily soluble in ethanol and ether, soluble in benzene, insoluble in water.  <\/p>\n<\/p>\n<h2 id=\"dl\">Toxicological data<\/h2>\n<p>\n     Reproduction: Female intramuscular TDLo: 65 mg\/kgSEX\/DURATION: female 8-32 week(s) after conception; Rabbit subcutaneous injection TDLo: 5 mg\/kgSEX\/DURATION: female 1 day(s) pre-mating;\n     <\/p>\n<h2 id=\"st\">Ecological data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"fz\">Molecular structure data<\/h2>\n<p><p>1. Molar refractive index: 92.52<\/p>\n<p>2. Molar volume (cm<sup>3<\/sup>\/mol): 286.0<\/p>\n<p>3. Isotonic specific volume (90.2K  ): 747.2<\/p>\n<p>4. Surface tensionForce (dyne\/cm): 46.5<\/p>\n<p>5. Polarizability (10-24cm3): 36.67<\/p>\n<\/p>\n<h2 id=\"js\">Compute chemical data<\/h2>\n<p><p>1. Reference value for hydrophobic parameter calculation (XlogP): None<\/P><\/p>\n<p>2. Number of hydrogen bond donors: 1<\/p>\n<p>3. Number of hydrogen bond acceptors: 3<\/p>\n<p>4. Number of rotatable chemical bonds: 1<\/p>\n<p>5. Number of tautomers: 10<\/p>\n<p>6. Topological molecule polar surface area 54.4<\/p>\n<p>7. Number of heavy atoms: 24<\/p>\n<p>8. Surface charge: 0<\/p>\n<p>9. Complexity: 635<\/p>\n<p>10. Number of isotope atoms: 0<\/p>\n<p>11. Determine the number of atomic stereocenters: 6<\/p>\n<p>12. Uncertain number of atomic stereocenters: 0<\/p>\n<p>13. Determine the number of chemical bond stereocenters: 0  <\/p>\n<p>14. Number of uncertain chemical bond stereocenters: 0<\/p>\n<p>15. Number of covalent bond units: 1<\/p>\n<\/p>\n<h2 id=\"xz\">Properties and stability<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"zc\">Storage method<\/h2>\n<p><p> This product should be kept sealed.  <\/p>\n<\/p>\n<h2 id=\"hc\">Synthesis method<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"yt\">Purpose<\/h2>\n<p>\n     For biochemical research.  Preparation of progesterone derivatives. \u200b\u200b\n     <\/p>\n<p>     extended-reading:https:\/\/www.bdmaee.net\/bdma\/<\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/31-7.jpg<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/920<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/567<\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2021\/05\/137-5.jpg<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/97<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44151<\/br>extended-reading:https:\/\/www.bdmaee.net\/n-butyltintrichloridemin-95\/<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/817<\/br>extended-reading:https:\/\/www.bdmaee.net\/fascat-4233-catalyst\/<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Structural formula Business number 01FG Molecular formu&#8230;<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[15043],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/47879"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=47879"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/47879\/revisions"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=47879"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=47879"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=47879"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}