{"id":42776,"date":"2023-04-17T10:05:03","date_gmt":"2023-04-17T02:05:03","guid":{"rendered":"https:\/\/www.newtopchem.com\/archives\/42776"},"modified":"2024-03-15T09:57:09","modified_gmt":"2024-03-15T01:57:09","slug":"n-formylmorpholine-production","status":"publish","type":"post","link":"http:\/\/www.newtopchem.com\/archives\/42776","title":{"rendered":"n-formylmorpholine production","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<h5><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">N-formylmorpholine is produced by the reaction of morpholine with formic acid. <\/span><span style=\"vertical-align: inherit;\">The reaction is carried out in the presence of a catalyst such as hydrochloric acid or sulfuric acid. <\/span><span style=\"vertical-align: inherit;\">The reaction is exothermic, and the product is a colorless water-soluble liquid. <\/span><\/span><\/h5>\n<h5><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">The reaction is usually performed as a batch process. <\/span><span style=\"vertical-align: inherit;\">Morpholine and formic acid are mixed in the presence of a catalyst and the reaction is heated to the desired temperature. <\/span><span style=\"vertical-align: inherit;\">The reaction is then allowed to proceed for a period of time before cooling and isolation of the product. <\/span><\/span><\/h5>\n<h5><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">The yield of the reaction is usually high and the product is of high purity. <\/span><span style=\"vertical-align: inherit;\">The reaction is relatively simple to perform and requires relatively inexpensive equipment. <\/span><\/span><\/h5>\n<h5><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">N-Formylmorpholine is a valuable chemical intermediate. <\/span><span style=\"vertical-align: inherit;\">It is used in the production of a variety of chemicals, including pharmaceuticals, pesticides, and plastics. <\/span><span style=\"vertical-align: inherit;\">Also used as a solvent and corrosion inhibitor. <\/span><\/span><\/h5>\n<h5><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">The production process of N-formylmorpholine is safe and environmentally friendly. <\/span><span style=\"vertical-align: inherit;\">The reaction does not produce any harmful by-products, and the products are not hazardous substances. <\/span><\/span><\/h5>\n<h5><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">The production of N-formylmorpholine is a growing industry. <\/span><span style=\"vertical-align: inherit;\">The demand for the product is increasing, and the price of the product is also increasing. <\/span><span style=\"vertical-align: inherit;\">The future of the industry is bright. <\/span><\/span><\/h5>\n<div class=\"bt-video-container\"><div style=\"width: 100%;\" class=\"wp-video\"><video class=\"wp-video-shortcode\" id=\"video-42776-1\" width=\"1200\" height=\"675\" preload=\"metadata\" controls=\"controls\"><source type=\"video\/mp4\" src=\"https:\/\/www.newtopchem.com\/video\/N-formylmorpholine.mp4?_=1\" \/>N-Formylmorpholine is a colorless to yellowish solid or liquid that is odorless.<br \/>It is used for desulfurization of natural gas, synthesis gas, flue gas, natural gas condensate and gasoline, etc.; it is the extraction solvent of petroleum aromatics device and can be used for recovery of aromatics by extractive distillation, which has good selectivity, thermal and chemical stability, non-toxicity and non-corrosion. It is a widely used solvent for recovering aromatics. It is an excellent non-protonic solvent with high solubility and selectivity for aromatics, and its mixtures have been successfully used in aromatics extraction process and butene thickening process.<br \/><\/video><\/div><\/div>\n<h5>N-formylmorpholine is an important Organic solvents and fine chemical raw materials. It can be used for desulfurization of natural gas, synthesis gas, flue gas, natural gas condensate and gasoline, etc.; it is the best extraction solvent for petroleum aromatics equipment, and aromatics can be recovered by extraction and distillation. It has good selectivity, thermal stability and Good chemical stability, non-toxic, non-corrosive.<\/h5>\n<h5>There are many ways to produce N-formylmorpholine, one of which is the production of N-formylmorpholine by morpholine enamine oxidation. The method is to dissolve morpholine and aldehyde with \u03b1-hydrogen in pyrimidine or dichloromethane at a molar ratio of 1:1.2, pass through oxygen and irradiate with a 500 W tungsten lamp for 40 min, morpholine and aldehyde undergo condensation reaction, and Dehydration produces enamine, then add 1.2 times the oxygen of morpholine to the reaction, and add hematoporphyrin as a photosensitizer to catalyze the oxidation reaction, the double bond of enamine is broken to generate N-formylmorpholine.<\/h5>\n<h5>Another production method is the formic acid production process. N-formylmorpholine is converted from formic acid morpholine. On the one hand, formic acid morpholine is neutralized with acid and alkali to form a salt, and N-formylmorpholine is dehydrated to produce N-formylmorpholine. Therefore, the product still has a part of salt, the purity is not high, and it can be used for a long time It can crystallize and block the pipeline; on the other hand, the raw material contains acid and water, and due to the saturation of N-formylmorpholine, the content of moisture, free acid and morpholine in the product is higher.<\/h5>\n<h5><\/h5>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>N-formylmorpholine is produced by the reaction of morph&#8230;<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[14541],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/42776"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=42776"}],"version-history":[{"count":1,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/42776\/revisions"}],"predecessor-version":[{"id":46428,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/42776\/revisions\/46428"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=42776"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=42776"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=42776"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}