Structural formula
Business number | 0132 |
---|---|
Molecular formula | CH6ClN3 |
Molecular weight | 95.53 |
label |
Carbamidamidine hydrochloride, Genetic engineering research reagents |
CAS number:50-01-1
MDL number:MFCD00013026
EINECS number:200-002-3
RTECS number:MF4300000
BRN number:3591990
PubChem ID:None
1. Properties: white or slightly yellow lumps
2. Melting point (℃): 181-183
3. Relative density (g/mL, 20/4 ℃): 1.354
4. Solubility: 228g can be dissolved in 100g water at 20℃, 76g can be dissolved in 100g methanol, and 24g can be dissolved in 100g ethanol. Almost insoluble in acetone, benzene and ether.
5. PH value (4% aqueous solution, 25℃): 6.4
The oral LD50 for rabbits is 500mg/kg. For protective methods, see thiosemicarbazide.
None
1. Molar refractive index: 12.89
2. Molar volume (cm3/mol): 37.9
3. Isotonic specific volume (90.2K ): 114.4
4. Surface tension (dyne/cm): 82.9
5. Polarizability (10-24cm3): 5.11
None
This product is relatively unstable and can be hydrolyzed in aqueous solution to form ammonia and urea, so its toxicity is the same as that of urea. Its derivatives are generally more toxic than ureas.
None
Using dicyandiamide and ammonium salt (ammonium chloride) as raw materials, conduct a melting reaction at 170-230°C to obtain crude guanidine hydrochloride, which can be refined to obtain the finished product.
1. Can be used as intermediates for medicines, pesticides, dyes and other organic synthesis. It can be used to synthesize 2-aminopyrimidine, 2-amino-6-methylpyrimidine, 2-amino-4,6-dimethylpyrimidine, and is used to manufacture sulfa drugs such as sulfadiazine, sulfamethylpyrimidine, and sulfadimethylpyrimidine. intermediate.
2. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate to form 2,4-diamino-6-hydroxypyrimidine, which is used to synthesize the anti-anemia drug folic acid. It can also be used as an antistatic agent for synthetic fibers.
3. It can also be used as a protein denaturant.
extended-reading:http://www.gengheonline.cn/archives/938extended-reading:http://www.gengheonline.cn/archives/category/products/page/134extended-reading:http://www.gengheonline.cn/archives/39156extended-reading:https://www.cyclohexylamine.net/strong-gel-amine-catalyst-ne500-dabco-strong-gel-amine-catalyst/extended-reading:https://www.bdmaee.net/u-cat-5002-catalyst-cas126741-28-8-sanyo-japan/extended-reading:http://www.gengheonline.cn/archives/45164extended-reading:http://www.gengheonline.cn/archives/677extended-reading:https://www.bdmaee.net/wp-content/uploads/2022/08/-RP205-Addocat-9727P-high-efficiency-amine-catalyst.pdfextended-reading:https://www.bdmaee.net/wp-content/uploads/2022/07/123-1.jpgextended-reading:https://www.bdmaee.net/wp-content/uploads/2022/08/N-Formylmorpholine-CAS4394-85-8-4-formylmorpholine.pdf
]]>